Imaging (PET/MRI) scanner, the researchers may potentially identify the source of pain ![]() Using the sigma-1 receptor (S1R) detectorĪnd experimental radiotracer FTC-146 and positron emission tomography/magnetic resonance Receptor drugs for the treatment of chronic pain. Generation and perpetuation of chronic pain conditions, others are investigating anti sigma-1 Several studies have implicated involvement of sigma-1 receptors in the Pain in these conditions, but the current diagnostic tools are limited in pinpointing theĪrea of origin. These nerve injuries or regions of nerve irritation are often the cause of When we are successful the role of cost-effective diagnostics in cancer will be markedly enhanced with better patient outcomes.Ĭhronic pain can result from injured or inflamed nerves, as occurs in people suffering from We are particularly interested in cell based therapies and immunotherapies where molecular imaging can help optimize these therapies. For the management of cancer we are focused on using imaging to optimize stratification of cancer patients, predicting response to therapy, and monitoring response to therapy and recurrence. The goal is to intercept cancer early so that patient outcomes can be markedly improved. In the early detection setting we are exploring multiple strategies that are pushing the limits of the fewest numbers of detectable cancer cells. Strategies are being tested in small animal models and are also clinically translated. Our goals are to detect cancer early and to better manage cancer through the use of both in vitro diagnostics and molecular imaging. Imaging agents for multiple modalities including small molecules, engineered proteins, and nanoparticles are under development and being clinically translated. Technologies such as positron emission tomography (PET), optical (fluorescence, bioluminescence, Raman), ultrasound, and photoacoustic imaging are all under active investigation. My laboratory is developing imaging assays to monitor fundamental cellular/molecular events in living subjects including patients. Vice Provost for Undergraduate Education.Office of Vice President for Business Affairs and Chief Financial Officer.Office of VP for University Human Resources.Stanford Woods Institute for the Environment. ![]() Stanford Institute for Economic Policy Research (SIEPR).Institute for Stem Cell Biology and Regenerative Medicine. ![]() Institute for Human-Centered Artificial Intelligence (HAI).Institute for Computational and Mathematical Engineering (ICME).Freeman Spogli Institute for International Studies.Stanford Doerr School of Sustainability.
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